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Intracytoplasmic Sperm Injection (ICSI) is a procedure performed in the lab where micromanipulation is used to insert one sperm cell into an egg. This procedure has been used worldwide for over two decades.
The male partner provides a fresh sample (or donor sperm is thawed) on the day of the woman’s retrieval, and the sample is prepped for use. ICSI is performed using two micropipettes attached to micromanipulators under a microscope. This procedure allows the embryologist to select the best sperm possible to fertilize each egg.